Frequency and determinants of Respiratory Failure in Acute Exacerbation of Chronic Obstructive Pulmonary Disease Patients: A Cross-Sectional Study

Abstract

Abstract

Background: Chronic obstructive pulmonary disease (COPD) is slowly and progressive disorder that is characterized by a permanent or partially reversible obstruction of airflow. A  COPD exacerbation can have a variety of clinical outcomes, from self-limited sickness to progressive respiratory failure.

Objective: To determine the prevalence and factors associated with respiratory failure among patients experiencing acute exacerbation of chronic obstructive pulmonary disease (COPD).

Objective:  The study was designed to evaluate maternal complications of emergency vs elective cesarean section for placenta previa.

Material and Methods: This cross-sectional study was conducted at the Department of Pulmonology in KhalifaGul Nawaz (KGN), MTI Bannu from January 2022 to December 2022, following approval from the institutional ethical committee. A total of 385 participants were enrolled in this study. Following the documentation of the physical examination and clinical history, various demographic details were noted. The data was analyzed through SPSS Version 25.0.

Results: A total of 385 patients presented with acute exacerbation of COPD were assessed. Out of which 258 were males (67%) and 127(32.9%) were females. In an acute exacerbation of COPD, the number of individuals presenting with respiratory failure was 138 (35.8%). out of which 91(23.6%) were males and 47(12.2%) were females. The age group of 51 to 60 years old had the highest number of individuals experiencing respiratory failure, which were 69 (17.9%).

Conclusion: : In the current study the frequency of respiratory failure in the participants presented with acute exacerbation was high. It is crucial to create efficient plans for stopping smoking and preventing COPD exacerbations in light of its effect on health care resources