Prevalence of Metabolic Syndrome in patients with psoriasis

Abstract

Objective: The study was planned to determine the frequency of metabolic syndrome in patients with psoriasis.

Place and duration of study: This study was conducted over a period of 6 months at the department of General Medicine, PAF Hospital, Islamabad, Pakistan from 1st January 2022 to 30 June 2022.

Materials and Methods: A total of 100 patients diagnosed with psoriasis using non-probability consecutive sampling were included in the study. Patient’s complete history was taken and thorough clinical examination was carried out at the time of inclusion.  This included the age, height, weight, blood pressure, waist circumference and duration of disease. Patients were advised fasting blood sugar, fasting triglycerides and fasting high density lipoproteins.  Metabolic syndrome was diagnosed if patients had ≥3 out of 5 criteria for the modified version of National Cholesterol Education Program Adult Panel III.

Results: Out of 100 patients of psoriasis, 37 (37%) patients had  metabolic syndrome while 63 (63%) had no metabolic syndrome. The mean±SD of all the parameters of metabolic syndrome were found raised in psoriatic patients than normal values both in male and females. No correlation was found between prevalence of MetS and duration of disease (p=0.16).

Conclusion: There is a high prevalence of metabolic syndrome in psoriatic patients that can lead to high cardiovascular events. Hence the patients having psoriasis must be screened on yearly basis for these controllable risk factors to reduce incidence of CV morbidity and mortality.