Effect of Chronic Kidney Disease on Thyroid Function

Abstract

Background: Chronic kidney disease results in downturn of glomerular filtration rate, which brings about nephropathic effect. The intensitifying nephropathy muddles the thyroid functions and turns down the iodide clearance, thus expedites the hypothyroidism.

Objective: The study aimed to link the chronic kidney disease with hypothyroidism.

Material and Methods: Our study design was cross-sectional. Chronic kidney disease patients were selected for thyroid profile (triodothyronine, thyroxine and thyroid stimulating hormone) testing. Statistical analysis was consummated on collected data, to check out the correlation between CKD and hypothyroidism.Chronic kidney disease is refers to by continuing urine defects structural irregularities or reduced excretory renal function connotative a loss of proper working nephrons. 

Results: We enrolled 105 patients suffering from CKD. Of them 62 were male patient and 43 were female. Our analysis concluded that 49, of whome 30 were male and 19 were female, had hypothyroidism. 23; 16 male and 7 female, were having subclinical hypothyroidism and low T3 was seen in 33 individuals, comprising of 16 male and 17 female patients.

Conclusion(s): It is evident, that there is substantial effect of CKD over thryroid function, as hypothyroidism, subclinical hypothyroidism and low T3 syndrome is more frequent in CKD patients. To fend off CKD, the thyroid function is needed to be kept under observation, so that good prognosis could be gained.