Occupational Variations in Vitamin D Status and its Correlation with Serum Lipids in Varying Glycemic Control Groups

Authors

  • Zaheer Abbas DMLS Scholar, Department of allied Health Sciences, The University of Lahore, Gujrat campus, Pakistan
  • Umair Waqas Lecturer, Imran Idress institute of Rehabilitation Sciences, Sialkot, Pakistan
  • Abid Ali Ali 3. Associate Professor, Department of Allied Health Sciences, the University of Chenab, Gujrat, Pakistan

Keywords:

Vitamin D, Sunlight, Diabetes mellitus, Lipid Profile

Abstract

Objective: The study focuses on the evaluation of the difference between the serum vitamin D3 levels, on the basis of sunlight exposure, in indoor and outdoor individuals and to find out the correlation between serum 1,25-OH-D and serum lipids of varying glycemic control subjects.

Methodology: We enrolled 221 participants. The serum 1,25-hydroxy-D3 was quantitated by immuno-fluorescence method. Blood HbA1c amount was analyzed by high performance liquid chromatography. Serum levels of cholesterol, triacylglycerols, high-density lipoprotein-cholesterol and low-density lipoprotein-cholesterol were estimated by spectrophotometric analysis. Very low-density lipoprotein cholesterol was computed using the Friedewald equation. The Statistical Package for Social Software 20.0 was chosen to statistically analyze the collected data.

Results: A significant dissimilarity in the levels of sun-born vitamin, the calcitriol, was calculated, among the sun-exposed and non-exposed group. The mean vitamin D value was measured higher in sun-exposure group than non-exposed to sun. There came to be known the interlink between glycemic control and vitamin D quantity. Serum vitamin D had an inverse relationship with serum cholesterol, triglycerides, LDL-C and VLDL-C, but a positive relation with HDL-C.

Conclusion: The present expanding insufficiency and deficiency of vitamin-D3 is bringing about the peril of prevalent dyslipidemia and poor glycemic control, hence jeopardizing the health of people. The current unforeseen falling off serum vitamin D levels in the principal part of the population, is needed to be overseen and treated accordingly

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Published

2023-12-20

Issue

Section

Original Articles