Occupational Variations in Vitamin D Status and its Correlation with Serum Lipids in Varying Glycemic Control Groups

Abstract

Objective: The study focuses on the evaluation of the difference between the serum vitamin D₃ levels, on the basis of sunlight exposure, in indoor and outdoor individuals and to find out the correlation between serum 1,25-OH-D and serum lipids of varying glycemic control subjects.

Methodology: We enrolled 221 participants. The serum 1,25-hydroxy-D₃ was quantitated by immuno-fluorescence method. Blood HbA1c amount was analyzed by high performance liquid chromatography. Serum levels of cholesterol, triacylglycerols, high-density lipoprotein-cholesterol and low-density lipoprotein-cholesterol were estimated by spectrophotometric analysis. Very low-density lipoprotein cholesterol was computed using the Friedewald equation. The Statistical Package for Social Software 20.0 was chosen to statistically analyze the collected data.

Results: A significant dissimilarity in the levels of sun-born vitamin, the calcitriol, was calculated, among the sun-exposed and non-exposed group. The mean vitamin D value was measured higher in sun-exposure group than non-exposed to sun. There came to be known the interlink between glycemic control and vitamin D quantity. Serum vitamin D had an inverse relationship with serum cholesterol, triglycerides, LDL-C and VLDL-C, but a positive relation with HDL-C.

Conclusion: The present expanding insufficiency and deficiency of vitamin-D₃ is bringing about the peril of prevalent dyslipidemia and poor glycemic control, hence jeopardizing the health of people. The current unforeseen falling off serum vitamin D levels in the principal part of the population, is needed to be overseen and treated accordingly